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Glossary

Allogeneic cell therapy

A therapy using cells derived from a donor to treat a different patient. Often intended to become an ‘off the shelf’ cell therapy product which uses cells derived from a single donor to treat many unrelated patients.

Alloimmunisation

The development of antibodies in response to foreign antigens.

Antibodies

An antibody, also known as an immunoglobulin, is a large Y-shaped protein produced by B lymphocytes that circulate in the blood and body fluids and can bind to and neutralise antigens as part of the body’s immune response.

Antigen

A foreign substance, usually a protein, which is capable of producing an immune response in the body.

Autologous cell therapy

A therapy using cells derived from a patient’s own body. This often involves the extraction of cells and an ‘ex vivo’ (outside the body) step of growing and multiplying them before transplanting them back into the patient.

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