A type of pluripotent stem cell derived from a non-pluripotent cell, typically an adult specialised cell such as skin cells. The adult specialised cell is manipulated in the laboratory, so that it becomes pluripotent and can make virtually any cell type in the body. These iPS cells also have the ability to self-renew, so are able to divide and produce copies of themselves indefinitely.
This is when iron accumulates in the body and can lead to organ damage. It is a concern among patients who receive frequent transfusions due to the amount of iron that builds up.